Chemical and Medical Metrology

home R&D Activities Chemical and Medical Metrology

The Division of Chemical and Medical Metrology is developing measurement standards and technologies in the area of chemistry, biology, medicine and ionizing radiations to improve people's quality of life. The division serves as the national reference laboratory especially in the fields of environmental protection, health care, and food safety. The established measurement standards are disseminated by providing CRMs, proficiency testing, and testing/calibration services for stakeholders including industries and public sectors.

Director: Dr. Sook-Kyung Kim (

Center for

  • Gas Analysis (Dr. Sangil Lee,
  • Bioanalysis (Dr. In Chul Yang,
  • Ionizing Radiation (Dr. Jungho Kim,
  • Analytical Chemistry (Dr. Yong-Hyeon Yim,
  • Medical Convergence Metrology (Dr. Yong Tae Kim,
Center for Gas Analysis

The Center for Gas Analysis establishes and maintains measurement standards in areas on greenhouse gases, ambient air pollutants (gases / particulate matter), emissions / process gases, indoor hazardous gases, workplace hazardous gases and energy gases. The center develops CRM(certified reference materials) to disseminates traceability, and provides measurement solutions for regulated substances to the inside and outside of the country.

Its current R&D project include the following subjects :

  • • Development of CRMs for greenhouse gases, air pollutants, energy gases, toxic gases, reactive gases, industrial specialty gases, pure gases
  • • Development of measurement technologies for ambient air pollutants and aerosol
  • • Development of measurement technologies for climate change inducing substances and their related properties
  • • Development of gas analysis techniques for improving industries’ measurement capabilities
  • • Type approval and audit tests of environmental measuring instruments (ambient/indoor/stack)

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Center for Bioanalysis

The Center for Bio-analysis is conducting researches on establishing ‘measurement standards for major bio-materials’ such as DNA, proteins, sugars and metabolites. We are also conducting researches to expand the established ‘measurement standards on bio-materials’ to ‘measurement standards on living things’ such as cells, microorganisms, and viruses and ‘measurement of complex life phenomena’ such as diseases, immunity, and biological reactions. Establishment of bio-measurement standards includes the development of primary measurement methods, ensuring international measurement equivalence, and the development and dissemination of reference materials on biological measurands.
Established bio-measurement standards are used to improve the accuracy and reliability of various bio-analyses such as clinical tests, molecular diagnostics, drug quality control, and food safety tests, thereby contributing to the improvement of the quality of life of the people.

Its current R&D project include the following subjects :

  • • Genetic and genomic measurement standards: Quantitative analysis of DNA and RNA, mutation, development of gene reference materials
  • • Protein and protein measurement standards: Quantitative analysis of proteins, development of protein reference materials, proteomics analysis
  • • Clinical Chemistry Measurement Standards: basic diagnostic tests, biomarkers, fetal and neonatal tests, serum and plasma standards
  • • Cell and microbial measurement standards: Measurements of cell growths and deaths, complete blood count (CBC) standards, quantitative microbiological analysis

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Center for Ionizing Radiation

The Center for Ionizing Radiation conducts research and development for establishing and disseminating national measurement standards on ionizing radiation. We establish the primary standards for radiation dose, radioactivity and neutron measurement. In the dissemination of the established standards we develop the calibration technology for radiation measurement equipments, the radioactivity CRMs, testing and certification technology for radiation device, and new techniques for precision measurements under harsh environments. We also provide calibration/testing services and CRMs necessary for the QC and QA of radiation measurement and safety that are required in the various fields such as hospitals, local environment analysis agencies, and radiation application research institutes and universities.

Its current R&D project include the following subjects :

  • • Establishment National standard on medical linear accelerator for high energy X-ray (6 MV, 10 MV, 18 MV)
  • • Development of water absorbed dose measurement technique for mammographic X-ray and PET / CT medical radiation measurement standard
  • • Establishment of standards for measurement of radioactivity in the air and development of next-generation measurement technology of gaseous radioactivity with ultra-short half-life.
  • • Development of materials/techniques for proficiency test and provision of proficiency test for domestic radioactive analysis institutions
  • • Establishment of thermal neutron standard and development of calibration technology of neutron dosimeter response

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Center for Analytical Chemistry

The Center for Analytical Chemistry establishes and maintains national measurement standards to improve the traceability and reliability of chemical analysis in the fields of environment, food, clinical, medical, industrial materials and product regulation. For this purpose, we have developed SI-traceable primary methods of analysis and demonstrated the equivalence of established standards through international comparisons between national metrology institutes. Based on the demonstrated calibration and measurement capabilities, various certified reference materials (CRMs) are developed and disseminated. As an effort to improve the quality of chemical analysis in the field laboratories, we also provide international and domestic proficiency testings using well-characterized samples with high homogeneity and robust reference values. In addition, we are developing novel measurement technologies to cope with future demands in analytical chemistry.

Its current R&D project include the following subjects :

  • • Development and maintenance of high purity elemental and organic primary standards thoroughly characterized with robust purity analysis methods
  • • Establishment of measurement standards for hazardous and nutrient chemicals in food and drug products and development of related CRMs
  • • Establishment of measurement standards for chemicals in environmental and oceanographic samples and development of related CRMs
  • • Establishment of measurement standards for hazardous and functional substances in industrial materials and development of related CRMs
  • • Development of advanced measurement technology and novel primary methods for ultratrace analysis, microscopic analysis and the realization of absolute quantitation

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Center for Medical Convergence Metrology

The aim of the Center for Medical Convergence Metrology is to become a world-leading research center in the field of ​​medical metrology and standards. In order to meet such objective, the center is pursuing the enhancement of the quality in medical big data by establishing the measurement standards for medical devices using fundamental physical quantities, developing the reproducible and reliable imagery through the quantification of the medical images, and developing new medical technologies for the diagnosis and therapy based on the precise measurement techniques.

Its current R&D project include the following subjects :

  • • Development of human body measurement standard
    • - Development of measurement standards for medical ultrasound and MRI SAR
    • - Development of bio-signal measurement technology
    • - Development of reliability evaluation technology including drug injection pump and blood pressure monitor
  • • Development of medical image quantification and standardization technology
    • - Development of quantitative technology for medical convergence: MRI, CT, PET, Ultrasound, etc.
    • - Phantom technology development of human tissue for fusion imaging equipment
    • - Development of MRI thermal imaging technology for treating diseases

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